abstract：:The expression of fibroblast growth factor 10 (FGF-10) has not been studied in human ovarian cortical follicles. The aim of the present study was to investigate the expression of FGF-10 in preantral follicles from fetuses, girls and women. Ovarian samples were obtained from 14 human fetuses at 21-33 gestational weeks ...

journal_title：Reproductive biomedicine online

authors： Oron G,Fisch B,Zhang XY,Gabbay-Benziv R,Kessler-Icekson G,Krissi H,Ben-Haroush A,Ao A,Abir R

更新日期：2012-10-01 00:00:00

abstract：:Gonadotrophin-releasing hormone (GnRH) antagonist rescue is performed by replacing a GnRH agonist with a GnRH antagonist in patients with rapidly rising serum oestradiol who are at risk of ovarian hyperstimulation syndrome (OHSS) during stimulation. It results in a rapid reduction in serum oestradiol, allowing for the...

journal_title：Reproductive biomedicine online

authors： Hill MJ,Chason RJ,Payson MD,Segars JH,Csokmay JM

更新日期：2012-09-01 00:00:00

abstract：:This worldwide web-based survey compared the clinical practice for luteal-phase supplementation (LPS) in stimulated IVF cycles to the current evidence-based literature. Eighty-four treatment centres in 35 countries, representing a total of 51,155 IVF cycles/year, responded. Vaginal progesterone alone was used for LPS ...

journal_title：Reproductive biomedicine online

authors： Vaisbuch E,Leong M,Shoham Z

更新日期：2012-08-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of vaginal natural progesterone on the prevention of preterm birth in IVF/intracytoplasmic sperm injection (ICSI) pregnancies. A single-centre prospective placebo-controlled randomized study was performed. A total of 313 IVF/ICSI pregnant patients were randomized into t...

journal_title：Reproductive biomedicine online

authors： Aboulghar MM,Aboulghar MA,Amin YM,Al-Inany HG,Mansour RT,Serour GI

更新日期：2012-08-01 00:00:00

abstract：:Oxygen derivatives that comprise the large family of reactive oxygen species (ROS) are actively involved in placental biology. They are generated at the maternal-fetal interface at the level of decidual, trophoblast and mesenchymal components. In normal conditions, ROS produced in low concentrations participate in dif...

journal_title：Reproductive biomedicine online

authors： Bevilacqua E,Gomes SZ,Lorenzon AR,Hoshida MS,Amarante-Paffaro AM

更新日期：2012-07-01 00:00:00

abstract：:There has been little research on the views and experiences of non-biological parents of sperm donor children. This paper reports the results of a survey of non-biological mothers and fathers. An online survey was designed and conducted by the Donor Sibling Registry, a US-based non-profit organization that supports th...

journal_title：Reproductive biomedicine online

authors： Frith L,Sawyer N,Kramer W

更新日期：2012-06-01 00:00:00

abstract：:Anti-Müllerian hormone (AMH) has emerged as an important marker of ovarian reserve. Its variation throughout the cycle, however, may still be a matter of debate. The objective of this study was to re-evaluate the intra-cycle fluctuations of AMH in individuals in a prospective clinical study with focus on the age-relat...

journal_title：Reproductive biomedicine online

authors： Overbeek A,Broekmans FJ,Hehenkamp WJ,Wijdeveld ME,van Disseldorp J,van Dulmen-den Broeder E,Lambalk CB

更新日期：2012-06-01 00:00:00

abstract：:The study aimed to examine: (i) the association between perception of infertility controllability and coping strategies; and (ii) the association between perception of infertility controllability and coping strategies to psychological distress, applying multivariate statistical techniques to control for the effects of...

journal_title：Reproductive biomedicine online

authors： Gourounti K,Anagnostopoulos F,Potamianos G,Lykeridou K,Schmidt L,Vaslamatzis G

更新日期：2012-06-01 00:00:00

abstract：:Some patients in IVF programmes repeatedly display an abnormal embryonic development characterized as soon as day 2 post fertilization by a high rate (>60%) of highly fragmented embryos (⩾40% of cytoplasmic fragments) leading to recurrent IVF failures. This study postulated that, for various maternal reasons, some emb...

journal_title：Reproductive biomedicine online

authors： Sermondade N,Delarouzière V,Ravel C,Berthaut I,Verstraete L,Mathieu E,Antoine JM,Mandelbaum J

更新日期：2012-04-01 00:00:00

abstract：:Quality management according to ISO 9001:2008 guidelines includes infertility care quality assessment and improvement. This study aimed to describe the development process of a questionnaire for infertility management. A literature review, qualitative interviews with experts and patients resulted in a content-valid an...

journal_title：Reproductive biomedicine online

authors： Van den Broeck U,Spiessens C,Dancet E,Bakelants E,Vrancken A,Demyttenaere K,Enzlin P,D'Hooghe T

更新日期：2012-03-01 00:00:00

abstract：:FOXO4 constitutes a coherent candidate gene associated with premature ovarian failure (POF) pathogenesis. This study sequenced the coding and exon-flanking regions of this gene in a panel of 116 POF patients and 143 controls of Tunisian origin. In both groups, the IVS2 + 41T > G sequence variant was identified. It is ...

journal_title：Reproductive biomedicine online

authors： Fonseca DJ,Garzón E,Lakhal B,Braham R,Ojeda D,Elghezal H,Saâd A,Restrepo CM,Laissue P

更新日期：2012-03-01 00:00:00

abstract：:When infertile women undergoing IVF or intracytoplasmic sperm injection (ICSI) have more than 20 mature oocytes retrieved, at least 15 oocytes are inseminated by their husband's spermatozoa. The extra oocytes are cryopreserved by vitrification. If the patients became pregnant and have healthy live births, the patients...

journal_title：Reproductive biomedicine online

authors： Cai LB,Qian XQ,Wang W,Mao YD,Yan ZJ,Liu CZ,Ding W,Huang J,Chai DC,Chian RC,Liu JY

更新日期：2012-02-01 00:00:00

abstract：:In stimulated IVF/intracytoplasmic sperm injection cycles, the luteal phase is disrupted, necessitating luteal-phase supplementation. The most plausible reason behind this is the ovarian multifollicular development obtained after ovarian stimulation, resulting in supraphysiological steroid concentrations and consecuti...

journal_title：Reproductive biomedicine online

authors： Humaidan P,Papanikolaou EG,Kyrou D,Alsbjerg B,Polyzos NP,Devroey P,Fatemi HM

更新日期：2012-02-01 00:00:00

abstract：:Today an accurate diagnosis of adenomyosis can be made thanks to progress in imaging techniques: sonography and magnetic resonance imaging (MRI). This has made it possible to clinically correlate the presence of adenomyosis to infertility. At the same time, a series of pathogenetic hypotheses have been presented to ex...

journal_title：Reproductive biomedicine online

authors： Campo S,Campo V,Benagiano G

更新日期：2012-01-01 00:00:00

abstract：:The aim of this research was to ascertain how the opportunities now open by the Greek legislation regarding assisted reproduction fits with Greek society and how it compares with the wider EU legal framework. A revision of the Greek legislation took place a few years ago, with two new Acts. The different issues that a...

journal_title：Reproductive biomedicine online

authors： Leon G,Papetta A,Spiliopoulou C

更新日期：2011-12-01 00:00:00

abstract：:From an economist's perspective, cross-border reproductive care (CBRC) reflects a global market economy bringing together the needs of patients and skills of doctors at an agreed price. From this perspective CBRC is neither wrong nor right, rather it reflects rational economic behaviour of couples to maximize their we...

journal_title：Reproductive biomedicine online

authors： Connolly M

更新日期：2011-12-01 00:00:00

abstract：:For some patients, the autotransplantation of a cryopreserved-thawed intact ovary might be the best option to preserve their reproductive potential after fertility-threatening treatment. The best procedure to successfully cryopreserve a human ovary without inflicting a devastating level of cryodamage is to date unknow...

journal_title：Reproductive biomedicine online

authors： Gerritse R,Beerendonk CC,Westphal JR,Bastings L,Braat DD,Peek R

更新日期：2011-12-01 00:00:00

abstract：:This article attempts to capture the dynamics of return reproductive tourism to the Middle East, based on ethnographic research undertaken at four different Middle Eastern locales (Egypt, Lebanon, United Arab Emirates and Arab America). Across the Middle Eastern diaspora, which is now vast, due to the disruptions of w...

journal_title：Reproductive biomedicine online

authors： Inhorn MC

更新日期：2011-11-01 00:00:00

abstract：:The association between endogenous LH concentrations during ovarian stimulation in a gonadotrophin-releasing hormone (GnRH) antagonist protocol and pregnancy likelihood was examined in a large combined analysis of individualized patient data obtained after treatment with recombinant FSH and a GnRH antagonist prior to ...

journal_title：Reproductive biomedicine online

authors： Griesinger G,Shapiro DB,Kolibianakis EM,Witjes H,Mannaerts BM

更新日期：2011-10-01 00:00:00

abstract：:The relationship between endogenous LH concentrations and ongoing pregnancy rates among normogonadotrophic patients undergoing ovarian stimulation in a gonadotrophin-releasing hormone antagonist protocol were examined. In the Engage trial, 1506 patients received corifollitropin alfa (150 μg) or daily recombinant FSH (...

journal_title：Reproductive biomedicine online

authors： Doody KJ,Devroey P,Leader A,Witjes H,Mannaerts BM

更新日期：2011-10-01 00:00:00

abstract：:In male infertility, complementary treatment with antioxidant-containing food supplements quadruples the spontaneous pregnancy rate and reduces the cost per pregnancy by 60%. ...

journal_title：Reproductive biomedicine online

authors： Comhaire F,Decleer W

更新日期：2011-09-01 00:00:00

abstract：:The potential advantages of being able to cryopreserve oocytes have been apparent for many decades. Technical difficulties associated with the unique properties of the mammalian oocyte initially retarded rapid development in this area but recent advances have overcome many of the problems. A stage has now been reached...

journal_title：Reproductive biomedicine online

authors： Gook DA

更新日期：2011-09-01 00:00:00

abstract：:Cryopreservation and density-gradient washing (DGW) are routinely used in infertility treatment. This study used quantitative immunofluorescence analysis to report how these techniques affect concentrations of the oocyte activation factor, phospholipase C zeta (PLCζ) in spermatozoa from fertile men. DGW significantly ...

journal_title：Reproductive biomedicine online

authors： Kashir J,Heynen A,Jones C,Durrans C,Craig J,Gadea J,Turner K,Parrington J,Coward K

更新日期：2011-08-01 00:00:00

abstract：:The purpose of the study was to evaluate whether a lower concentration of FSH or 2-h incubation with FSH would improve the outcome of in-vitro maturation of oocytes. The immature oocytes were obtained from FVB mice, and were allocated to four groups and incubated in the maturation media for 24 h. The maturation media ...

journal_title：Reproductive biomedicine online

authors： Lin YH,Hwang JL,Seow KM,Huang LW,Hsieh BC,Chen HJ,Tzeng CR,Bai CH

更新日期：2011-07-01 00:00:00

abstract：:Myomectomy is one of the commonest gynaecological operations. Laparoscopic myomectomy has emerged over the last two decades as a possible alternative to the traditional laparotomy. Most studies have revealed that the laparoscopic procedure is at least as safe as the open procedure as to the rate of complications and m...

journal_title：Reproductive biomedicine online

authors： Mattei A,Cioni R,Bargelli G,Scarselli G

更新日期：2011-07-01 00:00:00

abstract：:Microarray technology is a promising method for investigating gynaecological benign pathology. This systematic review examined various parameters of the design of these studies, the methods used and the gene outcome in these diseases. Electronic searches were performed in Medline (up to April 2009). An overall represe...

journal_title：Reproductive biomedicine online

authors： Verginadis I,Kosmas IP,Simos Y,Velalopoulou A,Korkontzelos I,Anogeianaki A,Charalampopoulos K

更新日期：2011-06-01 00:00:00

abstract：:The paper 'Robert G. Edwards and the Roman Catholic Church' by Benagiano and colleagues in this issue of Reproductive BioMedicine Online is a very important and timely article published by well-informed authors on the occasion of the long-awaited award of the Nobel Prize to a well-deserved scientist, Bob Edwards. I fo...

journal_title：Reproductive biomedicine online

authors： Serour G

更新日期：2011-06-01 00:00:00

abstract：:Advertising is a commonly used means of recruiting an egg donor within Australia. The aim of this study was to explore the experiences and outcomes of people's attempts to recruit an egg donor through advertising in a printed publication, Melbourne's Child. Individuals and couples who placed a new advertisement betwee...

journal_title：Reproductive biomedicine online

authors： Nowoweiski S,Matic H,Foster P

更新日期：2011-06-01 00:00:00

abstract：:This retrospective study investigated whether mid-luteal serum progesterone concentrations are associated with live birth rates in women with WHO group II anovulatory infertility undergoing ovulation induction. Data were from women (n=335) stimulated with gonadotrophins using a low-dose step-up protocol, of which wome...

journal_title：Reproductive biomedicine online

authors： Arce JC,Balen A,Platteau P,Pettersson G,Andersen AN

更新日期：2011-05-01 00:00:00

abstract：:This study evaluated whether anti-Müllerian hormone (AMH) was differentially expressed in cumulus (CC) and granulosa (GC) cells from large antral and pre-ovulatory follicles collected from individual follicles in women undergoing in-vitro maturation (IVM) or IVF treatment. Expression studies of AMH, AMH receptor 2, FS...

journal_title：Reproductive biomedicine online

authors： Grøndahl ML,Nielsen ME,Dal Canto MB,Fadini R,Rasmussen IA,Westergaard LG,Kristensen SG,Yding Andersen C

更新日期：2011-04-01 00:00:00

abstract：:This study assessed whether age-specific (as-) cutoffs for anti-Müllerian hormone (AMH) have higher specificity in reflecting ovarian reserve than non-age-specific (nas-) AMH values. as-AMH values were defined in 792 consecutive infertility patients by establishing as-quartiles of AMH within five age groups. Oocyte yi...

journal_title：Reproductive biomedicine online

authors： Barad DH,Weghofer A,Gleicher N

更新日期：2011-03-01 00:00:00

abstract：:This paper presents the Danish 10-year experience (1999-2009) with cryopreservation (n=386) and autotransplantation of ovarian tissue (n=18). Before applying the technique to humans, the method was thoroughly tested and validated. The cryoprotectant solution was chosen after histological evaluation of mouse and human ...

journal_title：Reproductive biomedicine online

authors： Rosendahl M,Schmidt KT,Ernst E,Rasmussen PE,Loft A,Byskov AG,Andersen AN,Andersen CY

更新日期：2011-02-01 00:00:00

abstract：:High daily doses of gonadotrophin-releasing hormone (GnRH) antagonists during the follicular phase of ovarian stimulation were associated with low implantation rates. To test if this occurred because of profound pituitary suppression, the pituitary response was suppressed with a high-dose GnRH antagonist and recombina...

journal_title：Reproductive biomedicine online

authors： Garcia-Velasco JA,Bennink HJ,Epifanio R,Escudero E,Pellicer A,Simón C

更新日期：2011-02-01 00:00:00

abstract：:This study presents the world’s largest series of over 20,000 oocytes tested for aneuploidies, involving chromosomes 13,16, 18, 21 and 22, providing the data on the rates and types of aneuploidies and their origin. Almost every second oocyte (46.8%) is abnormal, with predominance of extra chromatid errors predicting p...

journal_title：Reproductive biomedicine online

authors： Kuliev A,Zlatopolsky Z,Kirillova I,Spivakova J,Cieslak Janzen J

更新日期：2011-01-01 00:00:00

abstract：:Discussion about the ethics of human embryonic stem cell (ESC) research in the UK tends to be dominated by the divisive and potentially intractable issue of the moral status of the embryo. This can have the effect of silencing or marginalizing other concerns, especially in the context of public engagement with science...

journal_title：Reproductive biomedicine online

authors： Bahadur G,Morrison M,Machin L

更新日期：2010-12-01 00:00:00

abstract：:The elucidation of the metabolic requirements of human embryos in vivo or in vitro remains, despite being intensively investigated, a work in progress. The adoption of extended embryo culture to the blastocyst stage during the last decade has entailed new challenges. With the increased attention to culture media formu...

journal_title：Reproductive biomedicine online

authors： Wirleitner B,Vanderzwalmen P,Stecher A,Zech MH,Zintz M,Zech NH

更新日期：2010-12-01 00:00:00

abstract：:This article reports the results from a study of couples participating in a research protocol in which IVF/preimplantation genetic diagnosis (PGD) was available for non-medical sex selection. The study sought to characterize the moral attitudes and beliefs of couples actively pursuing IVF/PGD solely for purposes relat...

journal_title：Reproductive biomedicine online

authors： Sharp RR,McGowan ML,Verma JA,Landy DC,McAdoo S,Carson SA,Simpson JL,McCullough LB

更新日期：2010-12-01 00:00:00

abstract：:In this retrospective study, the utility of preimplantation genetic screening (PGS) in patients with advanced maternal age is evaluated. The patient population consisted of women aged 38-44years and included in a regular IVF programme with or without PGS analysis. Transfer rate, ongoing implantation rate and ongoing p...

journal_title：Reproductive biomedicine online

authors： Milán M,Cobo AC,Rodrigo L,Mateu E,Mercader A,Buendía P,Peinado V,Delgado A,Mir P,Simón C,Remohí J,Pellicer A,Rubio C

更新日期：2010-11-01 00:00:00

abstract：:Gentle ovarian stimulation protocols, such as 'mini-IVF', have several potential advantages over conventional IVF protocols, including less medication and fewer injections, producing fewer eggs, but eggs of higher quality. The particular 'mild' stimulation protocol called 'mini-IVF' is described. This protocol require...

journal_title：Reproductive biomedicine online

authors： Zhang J,Chang L,Sone Y,Silber S

更新日期：2010-10-01 00:00:00

abstract：:This study reports two clinical pregnancies and one live birth following the transfer of vitrified blastocysts developed from oocytes with neither zona pellucida nor corona cells. Two zona-free oocytes obtained from two patients of advanced maternal age undergoing minimal stimulation were normally fertilized after int...

journal_title：Reproductive biomedicine online

authors： Shu Y,Peng W,Zhang J

更新日期：2010-10-01 00:00:00